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Jena 2013 – scientific programme

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K: Fachverband Kurzzeitphysik

K 9: Laseranwendungen und Lasermaterialbearbeitung III

K 9.1: Talk

Thursday, February 28, 2013, 16:30–16:45, HS 4

a laser-driven nanosecond proton source for radiobiological studies — •jianhui bin1,2, klaus allinger1,2, walter assmann1, guido a. drexler3, anna a. friedl3, dieter habs1, peter hilz1, nicole humble4, daniel kiefer2, wenjun ma1, doerte michalskai4, michael molls4, sabine reinhardt1, thomas e. schmid4, olga zlobinskaya4, joerg schreiber1,2, and jan j wilkens41Faculty of Physics, Ludwig-Maximilians-Universitaet Muenchen, Am Coulombwall 1, 85748 Garching, Germany — 2Max Planck Institute of Quantum Optics, Hans-Kopfermann-Str. 1, 85748 Garching, Germany — 3Department of Radiation Oncology, Ludwig-Maximilians-Universitaet Muenchen, Schillerstr. 42, 80336 Muenchen, Germany — 4Department of Radiation Oncology, Technische Universitaet Muenchen, Klinikum rechts der Isar, Ismaninger Str. 22, 81675 Muenchen, Germany

Ion beams are relevant for radiobiological studies and for tumor therapy. In contrast to conventional accelerators, laser-driven ion acceleration offers a potentially more compact and cost-effective means of delivering ions for radiotherapy. Here we show that by combining advanced acceleration using nanometer thin targets and beam transport, truly nanosecond quasi-monoenergetic proton bunches can be generated with a table-top laser system, delivering single shot doses up to 7 Gray to living cells. Although in their infancy, laser-ion accelerators allow studying fast radiobiological processes as demonstrated here by measurements of the relative biological effectiveness of nanosecond proton bunches in human tumor cells.

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