Regensburg 2013 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 11: Posters: Statistical Physics in Biological Systems (joint with DY)
BP 11.19: Poster
Montag, 11. März 2013, 17:30–19:30, Poster B2
Evolution of increasingly complex filamentous molecules — •Philipp Zimmer1, Emanuel Worst2, Eva Wollrab2, Albrecht Ott2, and Karsten Kruse1 — 1Universität des Saarlandes, Theoretische Biologische Physik, Postfach 151150, 66041 Saarbrücken — 2Universität des Saarlandes, Biologische Experimentalphysik, Postfach 151150, 66041 Saarbrücken
On the young earth, molecules with increasing complexity evolved under prebiotic conditions. How the interplay of different, competing molecular species and the spontaneous generation of new ones eventually led to the formation of cells remains poorly understood. Here we investigate a mechanism of “biased variation” and show that it provides a way to generate more complex structures. In this mechanism certain variations of existing molecular species are more likely to occur than others. Combined with an exponential amplification, this process can generate increasing complexity. We investigate this mechanism using a stochastic model for the evolution of linear molecules and we present a DNA-based experimental realization.