Regensburg 2013 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 26: Posters: Biomaterials and Biopolymers (joint with CPP)
BP 26.4: Poster
Mittwoch, 13. März 2013, 17:30–19:30, Poster C
Spatio-Temporal Changes in Mechanical Properties of Extracellular Matrix of Hydra Magnipapillata — •Mariam Veschgini1, Suat Özbek2, Manfred Burghammer3, Thomas Holstein2, and Motomu Tanaka1 — 1Physical Chemistry of Biosystems, Physical Chemistry Institut, University of Heidelberg, 69120 Heidelberg, Germany — 2Center for Organismal Studies, Department of Molecular Evolution and Genomics, University of Heidelberg, 69120 Heidelberg, Germany — 3European Synchrotron Radiation Facility (ESRF), Grenoble Cedex 9 38053, France)
The extracellular matrix (ECM) of the freshwater polyp hydra, called mesoglea, is one of the early forms of ECM. Hydra mesoglea has a multilayered structure, which is dynamically changed during the development.
The main goal of this study is to investigate the time evolution of local elastic properties of isolated mesoglea by means of nanoindentation with an Atomic Force Microscopy (AFM).
The results indicate a clear change in the elasticity of mesoglea along the main body axis. Furthermore, the analysis of elasticity as a function of budding stage suggests the first sign of a turn-over from "soft" to "stiff" mesoglea during the growth and maturation of buds.
To further gain the local fine structure of mesoglea, the first grazing incidence small angle X-ray scattering experiments on isolated mesoglea were performed with a nano-focused beam (200 nm) at the European Synchrotron Radiation Facility (ESRF).