Regensburg 2013 – scientific programme

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BP: Fachverband Biologische Physik

BP 28: Focus session: Intracellular Spectroscopy

BP 28.6: Talk

Thursday, March 14, 2013, 11:00–11:15, H44

Plasmonic Nanoantennas for SERS on Supported Membranes — •Paul Kühler, Theobald Lohmüller, and Jochen Feldmann — Chair for Photonics and Optoelectronics, LMU München

We utilize plasmonically coupled gold triangles for Surface enhanced Raman scattering (SERS) measurements of a fluid lipid bilayer. First, large arrays of plasmonic nanoantennas made of gold triangles are prepared on a solid support by an improved colloidal lithography technique. Then, a fluid supported membrane is formed on the intervening glass substrate by vesicle fusion. We demonstrate the applicability of this platform for spectroscopic investigations by performing SERS measurements of molecules that are constituents of a fluid supported phospholipid membrane. Our method offers a tool to analyze lipid membranes and membrane components under physiological conditions without fluorescent labeling or static entrapment of the membrane molecules.