Regensburg 2013 – wissenschaftliches Programm

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CPP: Fachverband Chemische Physik und Polymerphysik

CPP 35: Poster: Biomaterials and Biopolymers (joint session BP/CPP)

CPP 35.2: Poster

Mittwoch, 13. März 2013, 16:30–18:30, Poster C

Nano-Mechanics of Type I Collagen Fibrils in Aqueous Solution — •Diana Voigt, Julia Hann, Eike-Christian Spitzner, and Robert Magerle — Chemnitz University of Technologie, Institut of Physics, Germany

We investigate purified type I collagen extracted from bovine hide. In aqueous solution, triple helices of collagen molecules (tropocollagens) form fibrils driven by hydrogen bonding processes. Single collagen fibrils, deposited on a silicon substrate, were exposed to an aqueous solution with controlled pH and salt concentration. We use in-situ multi-setpoint intermittent contact mode (MUSIC-Mode) atomic force microscopy for quantitative imaging of collagen fibrils and their mechanical properties in aqueous solution. Furthermore we control the electrochemical potential between the sample and the AFM probe.