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CPP: Fachverband Chemische Physik und Polymerphysik

CPP 9: Poster: Interfaces and Thin Films (joint session with DECHEMA and VDI)

CPP 9.23: Poster

Montag, 11. März 2013, 17:30–19:30, Poster C

The effect of salt ions on the protein adsorption at lipid membranes — •Holger Göhring, Michael Paulus, and Metin Tolan — Fakultät Physik/DELTA, Technische Universität Dortmund, D-44221 Dortmund

Lipid membranes serve in biological cells as boundaries between the intracellular and extracellular region. Many biological transport processes taking place at membranes are associated with the adsorption of proteins. Here the investigation of protein - membrane interactions is crucial for a deeper understanding of such processes. In the case of electrostatic interaction the screening effect of salt ions can be used to control the adsorption. The presented study investigates the protein adsorption to Langmuir films under the presence of different concentrations of salt ions. Langmuir films prepared on a liquid subphase are an ideal model for cell membranes. By varying the salt concentrations the electrostatic interaction between the films and proteins is altered. However, also the accumulation of ions at the Langmuir films has to be taken into account just as the different impact of the salts on the stability of the proteins. To regard those effects different salt ions are used during this study. The adsorption process is investigated by x-ray reflectivity (XRR) measurements, which allow the determination of the electron densities of thin layers at the liquid surface.