Regensburg 2013 – scientific programme
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O: Fachverband Oberflächenphysik
O 87: Focussed Session: Solid-liquid Interfaces III
O 87.10: Talk
Friday, March 15, 2013, 12:45–13:00, H31
Electrochemical infrared spectroscopy to induce and detect neurotransmitter exchange across a solid-liquid interface — •Neelima Paul1,3, Kenichi Ataka2, Joachim Heberle2, Peter Müller-Buschbaum3, and Martha Ch. Lux-Steiner1 — 1Helmholtz-Zentrum Berlin für Materialien und Energie GmbH, Hahn-Meitner-Platz 1, 14109 Berlin, Germany — 2Freie Universität Berlin, Department of Physics, Experimental Molecular Biophysics, 14195 Berlin, Germany — 3TU München, Physik-Department, LS Funktionelle Materialien, James-Franck-Str. 1, 85747 Garching, Germany
We present in-situ electrochemical-infrared spectroscopy data on voltage induced vibrational changes of neurotransmitter molecule, monosodium glutamate at a solid/liquid interface. For the polarised glutamate molecule, containing two deprotonated carboxylate groups and one protonated amine group at physiological pH, structural changes on application of different magnitudes of voltages at the solid electrode surface as well as molecular transfer events are resolved by surface-enhanced IR difference absorption spectroscopy (SEIDAS). Angular changes of bonds versus the surface normal have been determined because SEIDAS monitors only those vibrations whose dipole moment are oriented perpendicular to the solid surface. The application of positive and negative surface potentials (0.7 V) leads to the release of the glutamate molecules, which were initially adsorbed at the gold solid surface. This adsorption/release process is completely reversible. A possible application could be retinal implants.