Regensburg 2013 – scientific programme
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ST: Fachverband Strahlen- und Medizinphysik
ST 6: Advances in Radiation Therapy I
ST 6.3: Talk
Thursday, March 14, 2013, 15:40–16:00, H41
Characterization of the interaction between therapeutical carbon ions and bone-like materials and related impact on treatment planning — •Anna Eichhorn1, 2, Antonio Carlino3, Robert Kaderka1, Michael Krämer1, Chiara La Tessa1, Emanuele Scifoni1, and Marco Durante1, 2 — 1GSI Helmholtzzentrum für Schwereionen, Darmstadt, Germany — 2TU Darmstadt, Germany — 3University of Palermo, Italy
Radiotherapy is one of the most common and effective therapies for cancer. The treatment planning system for ions TRiP98 was developed at GSI, Darmstadt. In TRiP98, the interaction between primary radiation and tissue is modeled from experimental data measured in water and rescaled to other tissue. This approximation is not accurate enough for biological materials whose elemental composition besides density deviates significantly from water. The nuclear attenuation of carbon beams in bone-like materials was measured and an estimation of the fragmentation cross section was done. In parallel, the dose profile inhomogeneity predicted by TRiP98 at the interface between water and bones was investigated and measured at HIT (Heidelberg). A 3D treatment plan was delivered in a water phantom equipped with bone targets. Pin-point ionization chambers and X-ray dosimetric films were used for measuring the dose at different positions.
As a further step, the measured cross sections of carbon ions in bone have been implemented in TRiP98. The comparison of the dose profiles calculated with the standard and benchmarked versions of the treatment planning will give an estimate of the improvement.