Dresden 2014 – scientific programme

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BP: Fachverband Biologische Physik

BP 28: Protein structure and dynamics II

BP 28.1: Topical Talk

Wednesday, April 2, 2014, 15:00–15:30, HÜL 386

Single Molecule Mechanics of Proteins — •Matthias Rief — Physikdepartment der TUM, James-Franck-Str., 85748 Garching, Germany

The development of nano-mechanical tools like Atomic Force Microscopy and optical traps has made it possible to address individual biomolecules and study their response to mechanical forces. In my talk, I will show how single molecule mechanical methods can be used to study the folding and interaction of proteins. Examples include the folding of calmodulin as well as the interaction of the cytoskeletal protein filamin with transmembrane proteins.