Dresden 2014 – scientific programme

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BP: Fachverband Biologische Physik

BP 34: Imaging

BP 34.6: Talk

Thursday, April 3, 2014, 11:00–11:15, ZEU 250

Scanning probe magnetic spin imaging of the protein complex ferritin — •Dominik Schmid-Lorch, Thomas Häberle, Andrea Zappe, Friedemann Reinhard, and Jörg Wrachtrup — 3. Physikalisches Institut und Forschungszentrum SCoPE, Universität Stuttgart, Germany

We present a novel technique to image nanoscale magnetic fields. It is based on the nitrogen-vacancy (NV) center, a color center in diamond, which can be used as a novel magnetic field sensor by monitoring the Zeeman-shift of its spin sublevels [1]. Mounted to the tip of an atomic-force microscope (AFM), this atomic-sized color center promises to map magnetic fields with a resolution in the atomic range [2-3]. Being sensitive enough to detect single electron and nuclear spins in its close environment, it could enable imaging and structure determination of single biomolecules.

We will demonstrate imaging of magnetic resonance contrast agents with a resolution in the 10 nm range using this technique. Specifically, we have been able to image small ensembles of Ferritin, an iron storage protein complex [4], by detecting its spin noise with a scanning NV center probe. Beyond these results, we will present our progress towards imaging of single Ferritin complexes.

[1] G. Balasubramanian et al., Nature, Vol 455, 648-651 (2008)

[2] L. Rondin et al., Appl. Phys. Lett., Vol 100, 153118 (2012)

[3] P. Maletinsky et al., Nat. Nanotech., Vol 7, 320-4 (2012)

[4] M. Uchida et al., Magn. Reson. Med., Vol 60, 1073-1081 (2008)