Dresden 2014 – scientific programme

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BP: Fachverband Biologische Physik

BP 34: Imaging

BP 34.7: Talk

Thursday, April 3, 2014, 11:15–11:30, ZEU 250

The nitrogen vacancy in nanodiamonds as a bio-marker for resolving dynamics of bio molecules — •Torsten Rendler, Seoyoung Paik, Sany-Yun Lee, and Jörg Wrachtrup — 3. Physikalisches Institut, University of Stuttgart, Pfaffenwaldring 57, 70550 Stuttgart, Germany

Fluorescent probes are essential for bio imaging application. Therefore several different types of fluorescent markers like dye molecules, quantum dots and fluorescent nanodiamonds (fND) have been developed and studied for their purpose as bio-markers. Besides the superior long time stability of the fluorescent emissions, fNDs decorated with the nitrogen-vacancy (NV) color center exhibit another interesting property based on its electron spin system: The NV can probe both the orientation and strength of magnetic field in its environment [1]. This allows not only to locate the fND but also to detect its relative orientation to an external magnetic field in real time on a ms-timescale [2]. It also has been suggested that the rotational diffusion rate of nanodiamonds even in faster time scales are accessible [3]. These works motivate the development of experimental techniques to resolve the rotational diffusion of fNDs, which will also open the door for molecular motion tracing, like monitoring fast conformational changes of working bio molecules. As a preliminary test, we investigate the spin dynamics of NVs in freely rotating fNDs.

[1] Balasubramanian, G. et al., Nature 455, 648-651 (2008). [2] McGuinness, L. P. et al., Nat. Nanotech. 6, 358-363 (2011). [3] Maclaurin,D. et al.,PRL 108 240403(2012).