Dresden 2014 – scientific programme
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CPP: Fachverband Chemische Physik und Polymerphysik
CPP 42: Friction and Lubrication
CPP 42.2: Talk
Thursday, April 3, 2014, 09:45–10:00, ZEU 114
Structural arrangement of hyaluron and DPPC bilayer under high hydrostatic pressure — •Thomas Zander1, Florian Wieland1, Min Wang2, Akanksha Raj2, Vasyl Haramus1, Andra Dedinaite2, Per Claesson2, and Regine Willumeit1 — 1Helmholz-Zentrum Geesthacht, Institute of Materials Research, D-21502 Geesthacht — 2KTH Royal Technical Institute, Department of Chemistry, SE-100 44 Stockholm
Articular joints are bio-lubrication systems with the lowest friction coefficients found in nature. The friction coefficient is provided by the synovial fluid, which is an intricate composition of different macromolecules (e.g. phospholipids and hyaluronan) and which keeps the exceptional good lubrication properties even under high loads and shear rates. It is thought that the different constituents form complex structures in order to enable this low friction coefficients.
In order to gain information about the structure of the hyaluronan-phospholipid bilayer samples we performed X-Ray reflectivity measurements at different hydrostatic pressures (1bar - 2kbar). The obtained data clearly reveal the adsorption of hyaluronan to the phospholipid bilayer. Interestingly the structure of the hyaluronan-DPPC layer varies as the molecular weight of hyaluronan is changed. This is supported by DLS and surface-pressure isotherms which show also a stronger interaction with a decreasing molecular weight of hyaluronan.