Dresden 2014 – scientific programme

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CPP: Fachverband Chemische Physik und Polymerphysik

CPP 44: Charged Soft Matter I

CPP 44.9: Talk

Thursday, April 3, 2014, 11:45–12:00, ZEU 118

Elastic/viscoelastic properties of polyelectrolyte multilayer films (PLL/HA) as measured by AFM nano-indentation — •Johannes Hellwig and Regine von Klitzing — Stranski-Laboratorium, Department of Chemistry, TU Berlin, Strasse des 17. Juni 124, D-10623 Berlin

In recent years smart biomaterials have become a highly developing field of interest for biomedical applications, e.g. drug delivery(1). The layer-by-layer (LbL) technique (2) gives the opportunity to build up self assembled polyelectolyte multilayer films (PEM) with defined architecture, physical and chemical properties. PEM made of poly(L-lysine) (PLL) and hyaluronic acid (HA) were produced by using the LbL technique. Potential applications of these PEMs require controlling of the adhesion behaviour by tuning their elastic/viscoelastic properties. In this study elastic(3) and viscoelastic properties of LbL coated poly(L-lysine)/hyaluronic acid PLL/HA films were studied by colloidal probe atomic force microscopy. It was shown that the indentation modulus of PLL/HA films measured in different pH and ionic strength of the surrounding medium changes. Increasing the temperature shows a slight decrease in modulus at higher temperatures. Furthermore the viscoelastic film behaviour was measured and calculated by stress relaxation and creep compliance measurements.