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DY: Fachverband Dynamik und Statistische Physik
DY 4: Anomalous Diffusion
DY 4.6: Vortrag
Montag, 31. März 2014, 10:45–11:00, ZEU 146
Normal vs. anomalous transport by molecular motors in living cells — •Igor Goychuk1, Vasyl Kharchenko2, and Ralf Metzler1,3 — 1Institute for Physics and Astronomy, University of Potsdam, 14476 Potsdam-Golm, Germany — 2Institute of Applied Physics, NAS Ukraine, 40030 Sumy, Ukraine — 3Department of Physics, Tampere University of Technology, 33101 Tampere, Finland
Discovery of anomalously slow diffusion of submicron particles in living cells
provokes a number of questions, in particular, on active transport of such subdiffusing
nanoparticles by molecular motors. Can such transport be normal
or it is also anomalously slow? Can the same motors in the same cells realize both normal and
anomalous transport and under which conditions? We answer these intriguing questions [1] within a
non-Markovian generalization of standard Markovian continuous diffusion model of molecular motors
with two conformational states by taking into account slowly decaying memory effects caused by the
viscoelasticity of cytosol. Here we follow to and develop further a general approach to
anomalous Brownian motors [2] which is based on Generalized
Langevin Equation and its Markovian embedding [3].
Supported by DFG, Grant GO 2052/1-2
[1] Goychuk, I., Kharchenko, V., Metzler, R. arXiv:1309.6724 [physics.bio-ph] (2013);
[2] Goychuk, I. Chem. Phys. 375, 450 (2010); Goychuk, I., Kharchenko, V.
Phys. Rev. E 85, 051131 (2012); Kharchenko, V. and Goychuk, I. New J. Phys., 14, 043042 (2012);
Phys. Rev. E 87, 052119 (2013);
[3] Goychuk, I. Adv. Chem. Phys. 150, 187 (2012); Phys. Rev. E 80, 046125 (2009).