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Mainz 2014 – wissenschaftliches Programm

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ST: Fachverband Strahlen- und Medizinphysik

ST 1: Radiation Therapy & Dosimetry

ST 1.7: Vortrag

Montag, 24. März 2014, 18:15–18:30, RW 2

Toward Fluence-Based Dosimetry Using Fluorescent Nuclear Track Detectors — •Grischa Klimpki1,2, Julia-Maria Osinga2,3, Mark Akselrod4, Oliver Jäkel2,5,6, and Steffen Greilich21University of Heidelberg — 2German Cancer Research Center — 3PTB Braunschweig — 4Landauer Inc. — 5Heidelberg Ion-Beam Therapy Center — 6Heidelberg University Hospital

Ion-Beam Cancer Therapy offers high dose conformity to deep-seated tumors while having the ability to spare surrounding healthy tissue. However, organ movement and uncertainties in treatment planning hamper this advantage and call for reliable in-vivo verification tools. Therefore, we investigate in-vivo fluence-based dosimetry using biocompatible fluorescent nuclear track detectors (FNTDs) [1].

FNTDs are single aluminum oxide crystals doped with carbon and magnesium. They contain color centers that fluoresce after radiochromic transformation under ionizing radiation [2]. Information such as ion trajectory and kinetic energy can be assessed non-destructively using a confocal laser-scanning microscope [3].

Fluence-based dosimetry using FNTDs relies on accurate angular distribution determination of observed particle fields. Thus, we optimized the reconstruction of ion trajectories through the crystal volume. FNTDs have been irradiated with 90 MeV/u carbon ions at the Heidelberg Ion-Beam Therapy Center under well-defined angles which could be reproduced after detector readout.

[1] Osinga et al. ArXiv: 1310.3135v1 (2013). [2] Akselrod et al. Radiat. Meas. 46 (2011). [3] Greilich et al. Radiat. Meas. 56 (2013).

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