Berlin 2015 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 16: Posters: Cell adhesion, mechanics and migration

BP 16.33: Poster

Montag, 16. März 2015, 17:30–19:30, Poster A

Complex thermorheology of cells — •Enrico Warmt, Sebastian Schmidt, Tobias Kießling, Anatol Fritsch, Roland Stange, and Josef Käs — Universität Leipzig Faculty of Physics and Earth Sciences, Leipzig, Germany

Temperature has a reliable and nearly instantaneous influence on mechanical responses of cells. We measured thermorheological behaviour of eight common cell types within physiologically relevant temperatures and applied thermorheological time-temperature superposition to creep compliance curves. Our results showed that superposition is not a universal feature, and is only applicable in four of the eight cell types. Cells with more complex temperature responses transitioned around 36°C. Activation energies were calculated for all cell types, albeit cells with complex temperature responses do not fit the model. These results reveal broad insights into thermally sensitive stress-strain relations of various cell types.