Berlin 2015 – wissenschaftliches Programm

Bereiche | Tage | Auswahl | Suche | Aktualisierungen | Downloads | Hilfe

BP: Fachverband Biologische Physik

BP 23: Posters: Molecular Motors

BP 23.3: Poster

Dienstag, 17. März 2015, 14:00–16:00, Poster A

Towards synthetic molecular motors: a model study — •Amartya Sarkar and Alexander Mikhailov — Fritz Haber Institute, Berlin 14195, Germany

We study the model of a synthetic molecular motor, whose operation closely emulates that of real molecular motors. The motor is described in terms of an elastic network and is able to perform cyclic conformational motions which in turn is capable of uni-directionally transporting a filament. The mechano-chemical motions are due to energy supplied by the binding of a ligand, its conversion to a product, and the subsequent release of the product. Stochastic simulations of this model motor system under the conditions of both weak and strong coupling with the filament, under varying temperatures, has been performed. A continuous transition between two regimes of operation, from that a deterministic ratchet mechanism to a Brownian ratchet mechanism, has been demonstrated. Further it is shown that the motor can operate even under the influence of an opposing external force. Various statistical and mechanical properties of this model have been studied in detail. We consider a further reduced description of this model system which satisfy both microscopic reversibility and detailed balance and perform extensive statistical analysis of the dynamics.