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BP: Fachverband Biologische Physik

BP 49: Molecular motors

BP 49.4: Vortrag

Donnerstag, 19. März 2015, 17:45–18:00, H 1028

Segregation of diffusible and directionally moving particles on a polar filament — •Denis Johann, Debajit Goswami, and Karsten Kruse — Saarland University, Saarbrücken, Germany

Directed transport in living cells relies on the action of motor proteins. These enzymes can transform chemical energy into mechanical work and move directionally along filamentous tracks. At the same time, these filaments serve as a substrate for the binding of proteins performing other functions, but that also obstruct the motors’ motion. Motivated by the mobile cross-linker Ase1, we theoretically study a system of molecular motors in the presence of diffusible particles. Both the motors and the obstacles shuttle between the filament and its surrounding. Numerical simulations of this system show a segregation between motors and obstacles if the filament ends act as diffusion barriers for the obstacles. A phenomenological mean-field theory captures the essential effects observed in the simulations [1].

[1] Johann, Goswami, and Kruse, Phys. Rev. E 89, 042713 (2014)