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BP: Fachverband Biologische Physik

BP 9: Biomaterials and Biopolymers I (joint BP/CPP)

BP 9.4: Vortrag

Montag, 16. März 2015, 15:15–15:30, EB 202

Hydrodynamic Slip on DNA in Nanopore Translocation Experiments — Lukas Galla¹, •Andreas J. Meyer¹, Andre Spiering¹, Andy Sischka¹, Michael Mayer², Adam R. Hall³, Peter Reimann¹, and Dario Anselmetti¹ — ¹University of Bielefeld, Germany — ²University of Michigan, USA — ³Wake Forest University School of Medicine, USA

In a recent paper, we reported on the observation of hydrodynamic slip on DNA by optical tweezers-controlled translocation experiments in solid-state and lipid-coated nanopores [1]. After a short introduction to the performed experiments, I will present our theoretical model describing the dominating electrohydrodynamic effects, with particular emphasis on the hydrodynamic slip boundary condition.

By solving the Poisson-Nernst-Planck and Stokes equations using finite element methods it is possible to gain insight into the influence of nanopore geometry and composition on translocation experiments. Furthermore, these continuous models of electrohydrodynamics can serve as an appropriate basis for dynamic DNA simulations.

[1] L. Galla, A. J. Meyer, A. Spiering, A. Sischka, M. Mayer, A. R. Hall, P. Reimann, and D. Anselmetti (2014). Hydrodynamic slip on DNA observed by optical tweezers-controlled translocation experiments with solid-state and lipid-coated nanopores. Nano Letters, 14(7), 4176-4182.