Berlin 2015 – scientific programme
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CPP: Fachverband Chemische Physik und Polymerphysik
CPP 41: Optical and Nonlinear Optical Properties I (joint session DF, CPP)
CPP 41.4: Talk
Wednesday, March 18, 2015, 10:40–11:00, EB 407
TiO2 coated Whispering Gallery Mode (WGM) Resonators for Label-free Biosensing — •Fabian Ruf1, Sarah Krämmer1, Christoph Vannahme2, Antonina Vigovskaya3, Ljiljana Fruk3, Anders Kristensen2, and Heinz Kalt1 — 1Institute of Applied Physics, Karlsruhe Institute of Technology (KIT), Germany — 2Department of Micro- and Nanotechnology, Technical University of Denmark (DTU), Denmark — 3DFG-Centre for Functional Nanostructures CFN, Karlsruhe Institute of Technology (KIT), Germany
Biosensors for label-free detection offer a huge variety of applications in life sciences and medicine since they facilitate point-of-care diagnostics. We use goblet-shaped polymeric high-Q WGM microresonators fabricated within a low-cost manufacturing process also suitable for mass production. After fabrication the polymeric resonators are coated with titanium dioxide using sputter deposition techniques. The sensitivity as figure of merit is given here by the size of the shift of a resonant mode when the surrounding of the resonator changes. Finite element simulations predict a significantly increased sensitivity for resonators coated with TiO2. Moreover, titanium dioxide is a well-suited platform for functionalization with dopamine derivates. The use of antibody-protein binding processes is expected to enable the specific detection of proteins and antibodies interesting for medical analysis.