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Berlin 2015 – wissenschaftliches Programm

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CPP: Fachverband Chemische Physik und Polymerphysik

CPP 55: Flow-Induced Structures in Complex Fluids (with DRG, Deutsche Rheologische Gesellschaft, and DY)

CPP 55.7: Vortrag

Mittwoch, 18. März 2015, 16:45–17:00, C 264

Clusters formation in microcirculationOthmane Aouane1,2,3, Marine Thiebaud2, Chaouqi Misbah2, and •Christian Wagner11Department of Experimental Physics, Saarland University, 66123 Saarbrücken, Germany — 2Université Grenoble Alpes, LIPHY, F-38000 Grenoble, France — 3LMPHE, URAC 12, Faculte des Sciences, Rabat, Morocco

We investigate numerically the flow of deformable objects such as vesicles and red blood cells (rbcs) in micro-channels. We focus on understanding the phenomena behind the formation of small train of cells (called clusters) that occurs in the microcirculation. We consider the rbc in 2D as a closed deformable and non-permeable membrane encapsulating an inner fluid and suspended in an outer fluid. The membrane total force is composed from a bending force, a tension force to fulfill the area conservation constraint, and a cell-cell interaction force to reproduce the depletion forces due to the effect of the plasma macromolecules such as fibrinogen. The cells are placed in a confined geometry (two parallel walls) and subjected to a Poiseuille flow. The inner and outer fluids obey to Stokes equations. This equations are solved using the boundary integral formulation. We observe that two kind of clusters exist namely: i) hydrodynamical clusters, and ii) polymer induced clusters. We notice that there is an interplay between the confinement and the formation/destruction of hydrodynamical clusters. The polymer induced clusters are more robust and remain stable independently from the confinement.

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