Berlin 2015 – wissenschaftliches Programm
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DS: Fachverband Dünne Schichten
DS 20: Focussed Session: In-situ optical spectroscopy
DS 20.6: Vortrag
Mittwoch, 18. März 2015, 12:00–12:15, H 0111
Microfluidic cells in IR-microscopy for biosensing — •Christoph Kratz1, Tom W. H. Oates1, Dirk Janasek2, and Karsten Hinrichs1 — 1Leibniz-Institut für Analytische Wissenschaften -ISAS- e.V., 12489 Berlin, Germany — 2Leibniz-Institut für Analytische Wissenschaften -ISAS- e.V., 44139 Dortmund, Germany
A novel flow cell platform system for investigations of solid/liquid-interfaces combining expertise in the fields of in situ IR-spectroscopy, enhancement substrates and microfluidics will be presented.
The versatile investigation technique of in situ IR spectroscopy which has been applied in various studies of technologically relevant thin films as e.g. smart polymer brushes will be supported by surface enhanced methods (surface enhanced infrared absorption, SEIRA) to increase sensitivity for biosensing. The high potential of the presented technique lies in a label-free investigation with the possibility e.g. to monitor chemical and structural changes of molecules and proteins via the interpretation of absorption bands of specific molecular vibrations using adequate optical.