Berlin 2015 – scientific programme
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DY: Fachverband Dynamik und Statistische Physik
DY 29: Statistical Physics of Biological Systems - Part II (joint session BP/DY/CPP)
DY 29.1: Talk
Wednesday, March 18, 2015, 09:30–09:45, H 1028
Pinned polymer loops in external field: how to align chromosomes for recombination? — Yen Ting Lin1, Daniela Frömberg1, Wenwen Huang1, Petrina Delivani2, Mariola Chacón2, Iva Tolic2, Frank Jülicher1, and •Vasily Zaburdaev1 — 1MPI for the Physics of Complex Systems, Dresden, Germany — 2MPI of Molecular Cell Biology and Genetics
Chromatin movement and structure are central to many processes in cells such as mitosis, replication, and transcription, where physical properties of the chromatin fiber play an essential role. Motivated by the problem of chromosome alignment and recombination during meiosis we solve for the statistics of a pinned polymer ring in an external force field. We predict how the contact probability between two rings depends on the ratio of the force to the intrinsic noise level and how it changes upon addition of new recombination spots. Due to the underlying loop topology, our theoretical results are readily applicable to the description of bacterial DNA and polymer brushes.