Berlin 2015 – wissenschaftliches Programm

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MA: Fachverband Magnetismus

MA 49: POSTER II

MA 49.5: Poster

Donnerstag, 19. März 2015, 15:00–18:00, Poster A

DNA origami as a microstructural tool for magnetic nanoparticle ordering — •Marianne Bartke and Andreas Hütten — Center for Spinelectronic Materials and Devices, Physics Department, Bielefeld University, Germany

Superparamagnetic beads have numerous applications within microfluidic systems, i.e. as mobile substrates, binds or magnetic labels, as well as to transport and separate analytes. Recently, the use of beads as self-assembling matter has attracted attention. Due to rotating homogeneous magnetic field, beads rapidly form ordered monolayers. If there is no magnetic field, the cluster structures rapidly disassemble. This work presents a method to prevent the decay of monolayers in the absence of a magnetic field employing DNA double strand *bridges* that connect adjacent particles. DNA with biotin can be linked to streptavidin coated magnetic beads, thus resulting in a DNA layer around these beads. These strands are complementary to a linker-DNA which induces a hybridization into DNA double strands. This hybridization between the linker strands and the oligonucleotides leads to a solidification of the monolayer that originally has been produced and stabilized by the external rotating magnetic field. The DNA bridges can be broken through controlled temperature change. Futhermore, DNA strands can also facilitate the creation of blocks of superparamagnetic cobalt nanoparticles by means of DNA origami. These new DNA stabilized superparamagnetic structures are auspicious innovations for DNA analysis and production of photonic crystal.