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P: Fachverband Plasmaphysik

P 11: Low Temperature Plasmas I

P 11.1: Hauptvortrag

Dienstag, 3. März 2015, 14:00–14:30, HZO 30

Cold atmospheric plasmas in medicine: basic mechanisms and practical applications — •Thomas von Woedtke — Leibniz-Institut für Plasmaforschung und Technologie e.V. (INP Greifswald), Felix-Hausdorff-Str. 2, 17489 Greifswald — Ernst-Moritz-Arndt-Universität Greifswald, Universitätsmedizin, 17475 Greifswald

Plasma medicine has been developed as innovative medical research field during the last years. The direct application of plasma as part of therapeutic concepts is most promising in dermatology, plastic surgery or dentistry, and is up to now focused on tissue regeneration, infected and/or chronic wounds as well as infective and inflammative skin diseases. Another field of big interest is oncology. To establish cold atmospheric pressure plasma sources as medical devices, detailed understanding of plasma action on living systems is indispensable. It was found that biological plasma effects are significantly caused by plasma induced changes of the liquid environment of cells and that redox-active species generated in or transferred into liquid phases by plasma treatment play a dominating role in transmission of biological plasma effects. Based on these fundamental insights the huge field of redox biology has been opened for basic research in plasma medicine because plasma generated redox-active species are the same as occurring in living cells as part of regular physiological and biochemical processes. This will contribute to consolidate a sound scientific basis of plasma medicine and will help to assess and control both further chances but also possible risks of plasma application in medicine.