Hannover 2016 – scientific programme
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Q: Fachverband Quantenoptik und Photonik
Q 59: Poster: Symposium Biomedical Optics (SYBO)
Q 59.4: Poster
Thursday, March 3, 2016, 16:30–19:00, Empore Lichthof
Separation of the reduced scattering and absorption coefficients of layered media using an enhanced integrating sphere setup — •Florian Bergmann, Florian Foschum, and Alwin Kienle — Institut für Lasertechnologien in der Medizin und Meßtechnik, Ulm, Deutschland
The integrating sphere is a well-known "golden standard method" to estimate optical properties of biological tissue. In contrast to other standard methods like spatially resolved-, time resolved- or temporal frequency resolved reflectance the integrating sphere setup allows the study of samples having small volumes.
Our enhanced integrating sphere setup using a layered GPU Monte Carlo simulation of light propagation for evaluation enables the separation of the reduced scattering µs′ and absorption µa coefficients in a spectral range of 400 to 1700 nm. Validation of the setup was done by preparation of epoxy resin phantom slabs with well-known optical properties in a range of 0.5 mm−1 < µs′ < 30 mm−1 and 10−3 mm−1 < µa < 10 mm−1. The results were compared with semi-infinite phantoms having the same properties as the slabs using other standard methods.
The next step is to separate the reduced scattering and absorption coefficients of layered biological samples like tissue.