Regensburg 2016 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 16: Posters - Computational Biophysics

BP 16.6: Poster

Montag, 7. März 2016, 17:30–19:30, Poster C

Opposite Translocation of Long and Short Oligomers Through a Nanopore — •Thomas Töws, Sebastian Getfert, and Peter Reimann — Fakultät für Physik, Universität Bielefeld, 33615 Bielefeld, Germany

We consider elongated cylindrical particles, modeling e.g. DNA fragments or nanorods, while translocating under the action of an externally applied electric potential through a solid-state nanopore. Particular emphasis is put on the concomitant potential-energy landscape due to the complex interplay of various electrohydrodynamic effects beyond the realm of small Debye lengths. We find that the net potential energy difference across the membrane may be of opposite sign for short and long particles of equal diameters and charge densities (e.g. oligomers). Thermal noise thus leads to biased diffusion through the pore into opposite directions. The specific particle length at which this transport inversion occurs can be controlled by means of a membrane gate electrode.