Regensburg 2016 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 49: Posters - Cell Mechanics and Migration & Physics of Cancer

BP 49.9: Poster

Mittwoch, 9. März 2016, 17:00–19:00, Poster C

Transport of micro-objects by amoeboid cells — •Manuel Frey, Oliver Nagel, Matthias Gerhardt, and Carsten Beta — Institute of Physics and Astronomy, University of Potsdam, Potsdam, Germany

The transport and positioning of micron-sized objects in complex geometries is often accomplished by fluid flow. However, under geometric constrains, like dead end structures, this is difficult to achieve. An alternative approach would be the use of magnetic or optical tweezers. Yet these techniques require a lot of time to rearrange many objects, since it has to be done one by one. Here, we propose a novel approach to move micron-sized objects in confined geometries, exploiting the chemotactic behavior of single cells. We use cells of the social amoeba Dictyostelium discoideum to transport objects of different sizes and shapes. Both chemotactic movement in artificial gradients as well as the endogenous aggregation of this microorganism can be exploited to achieve different transport tasks. In particular, cells may act individually on small particles but they can also transport larger objects in a collective effort.