Regensburg 2016 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 50: Posters - Cell Adhesion

BP 50.1: Poster

Mittwoch, 9. März 2016, 17:00–19:00, Poster C

Adhesion of oral bacteria to titanium surfaces of different roughness measured by single-cell force spectroscopy — •Kordula Schellnhuber, Christian Spengler, Nicolas Thewes, and Karin Jacobs — Department of Experimental Physics, Saarland University, 66041 Saarbrücken

Bacteria adhere to virtually all surfaces and promote the formation of biofilms. In the oral cavity, these initial biofilms may lead to plaque and consequently to severe health problems. Therefore, understanding and controlling the process of bacterial adhesion to oral implants is of great importance for material science and medicine. A common material for dental prostheses is titanium due to its robustness and high biocompatibility with various tissues. We use single-cell force spectroscopy to study the adhesion of Streptococcus mutans to titanium surfaces of different roughness. In addition, we compare the bacterial adhesion to titanium with the adhesion to very smooth samples of hydroxyapatite, the mineral component of teeth. Furthermore, we investigate the adhesion of Streptococcus mutans to real oral biofilms of different ages.