Regensburg 2016 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 53: Posters - Statistical Physics of Biological Systems

BP 53.11: Poster

Mittwoch, 9. März 2016, 17:00–19:00, Poster C

Coarse-Grained Interacting Particle Models for Chromatin Remodeling — •Michael Wolff, Johannes Nübler, and Ulrich Gerland — Physik-Department TU München, James-Franck-Straße 1, 85748 Garching

To explore the action of remodeling mechanisms on nucleosome patterns, we are studying physical models for one-dimensional interacting particle systems under the influence of additional agents actively displacing or evicting the particles. We characterize the connections between the mechanics of remodelers and the arising patterns, including non-equilibrium steady states with non-zero entropy production. We compare our modeling results, for example the formation of clusters, to nucleosome patterns obtained under varying experimental conditions with the aim to identify biologically relevant mechanisms.