Regensburg 2016 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 57: Membranes and Vesicles I

BP 57.5: Vortrag

Donnerstag, 10. März 2016, 10:45–11:00, H43

Structure and dynamics of phospholipid vesicles around the main phase transition — •Beate Brüning¹, Ramsia Sreij¹, Bela Farago², and Thomas Hellweg¹ — ¹Bielefeld University, Bielefeld, Germany — ²Institut Laue-Langevin, Grenoble, France

We use complementary scattering probes to study the molecular and structural reorganization of unilamellar 1,2-dimyristoyl-sn-glycero-3-phosphatidylcholine (DMPC) vesicles undergoing the phospholipids main phase transition. Effects on vesicle morphology and collective shape fluctuations are hierarchically interlinked. We cover length scales from molecule distances to an ensemble of vesicles in solution, and time scales ranging from ns to ms. We find temperature-induced changes in the lipid chain order and bilayer thickness are reflected most strongly in curvature changes and shape fluctuations, rather than in inter-vesicle lipid exchange processes. We comment on the implications for vesicle-membrane budding processes.

[1] Structure and dynamics of phospholipid vesicles around the main phase transition (submitted).