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Regensburg 2016 – scientific programme

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CPP: Fachverband Chemische Physik und Polymerphysik

CPP 50: Wetting, Nano- and Microfluidics I (joint session CPP/DY, organized by CPP)

CPP 50.10: Talk

Thursday, March 10, 2016, 12:15–12:30, H42

Compact nanosensors probe microdroplets — •Julian Schütt1, Felix Zörgiebel1,2, Bergoi Ibarlucea1,2, Sebastian Pregl1,2, Daijiro Nozaki1, Walter Weber2,3, Thomas Mikolajick2,3,4, Larysa Baraban1,2, and Gianaurelio Cuniberti1,21Max Bergmann Center of Biomaterials and Institute for Materials Science, Dresden University of Technology, Budapesterstrasse 27, 01069 Dresden, Germany — 2Center for Advancing Electronics Dresden, 01062 Dresden, Germany — 3Namlab GmbH, Nöthnitzerstraße 64, 01187 Dresden, Germany — 4Institute for Semiconductors and Microsystems, TU Dresden, 01062 Dresden

Smart combination of nanosensors and droplets based reactors represents a powerful tool for monitoring and high throughput analysis of the kinetics of biological and chemical reactions, staying miniaturized, highly sensitive and optically label-free. Here we present a first demonstration of droplets microfluidics with the compact silicon nanowire field effect transistor (SiNW FET) on a single chip for in flow electrical detection of aqueous reactor-drops. Apart from detection events, we chemically probe the content of numerous droplets in a row as independent events (up to ten thousands), and resolve the pH values and ionic strength of the solution, resulted in a change of a source-drain current through the nanowires. Optic-less and noninvasive measurements of these parameters in aqueous droplets have a great impact on the area of biodetection and bioanalytics as a high throughput screening tool for pathogens, drug assays, and evaluation of the enzymatic activities.

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