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Dresden 2017 – scientific programme

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AKBP: Arbeitskreis Beschleunigerphysik

AKBP 1: New Accelerator Concepts I

AKBP 1.11: Talk

Monday, March 20, 2017, 17:45–18:00, MOL 213

Optimization of the lateral and depth dose profile in the course of a small animal irradiation with laser-accelerated protons — •L. Gaus1,3, E. Beyreuther1, F.-E. Brack1,3, L. Karsch2, S. Kraft1, F. Kroll1,3, J. Metzkes1, J. Pawelke1,2, H.-P. Schlenvoigt1, M. Schürer2, K. Zeil1, and U. Schramm1,31Helmholtz-Zentrum Dresden-Rossendorf — 2Oncoray, National Center for Radiation Research in Oncology, Dresden — 3Technische Universität Dresden

Laser-driven ion acceleration has been considered a potential alternative for conventional accelerators and thus could provide a more compact and cost-efficient particle therapy solution. The beam properties of laser accelerated beams strongly differ from quasi-continuous beams. They exhibit fs to ps bunch length, carry up to 1013 particles with broad energy spectrum and are highly divergent.

The current driving question is whether pulsed proton beams obtain an equivalent biological efficacy compared to quasi-continuous beams in the case that a living organism is irradiated. Therefore, a small animal irradiation will be undertaken. That requires a homogeneous lateral and depth dose distribution, proton energies in the range of 25 MeV and dose rates in the order of Gy/min with a high degree of reproducibility. The experiment will be performed with the 600 TW beam of the Dresden laser acceleration source Draco.

This talk focuses on the characterization and optimization of the depth dose distribution as well as on the optimization of the target alignment procedure to provide the necessary dose rate.

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