Dresden 2017 – scientific programme

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BP: Fachverband Biologische Physik

BP 19: Posters - Computational Biophysics

BP 19.8: Poster

Tuesday, March 21, 2017, 14:00–16:00, P1A

Optical-tweezer controlled translocation of DNA-bound proteins in MoS2 nanopores — •Andreas J Meyer and Peter Reimann — Universität Bielefeld, Germany

Atomic monolayer MoS2 membranes promise great sensitivity improvements in nanopore experiments compared to commonly used, much thicker silicon-nitride membranes.

We study the translocation dynamics of DNA and DNA-bound proteins in ultra-thin MoS2 nanopores. Employing a worm-like chain model and Brownian dynamics we examine effects like two-state hopping and force hystereses, as were previously reported in SiN nanopores [1].

[1] A. Spiering, S. Getfert, A. Sischka, P. Reimann, and D. Anselmetti, Nano Lett., 11, 2978 (2011)