Dresden 2017 – scientific programme

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BP: Fachverband Biologische Physik

BP 38: Membranes and Vesicles I

BP 38.6: Talk

Wednesday, March 22, 2017, 11:30–11:45, HÜL 386

Measurements of lateral diffusion of phospholipids in the artificial cell membrane using diamond nanomagnetometry — •Farida Shagieva, Ya Wang, Zhiqin Chu, Andrea Zappe, Felipe Favaro de Oliveira, Andrej Denisenko, Amit Finkler, and Jörg Wrachtrup — 3rd Institute of Physics, University of Stuttgart, Stuttgart, Germany

Nuclear magnetic resonance (NMR) spectroscopy is serving as a powerful tool in physics and life sciences, but is limited by macroscopic sample quantities (several micrometers). Most recently, the shallow nitrogen vacancy centres underneath the surface of diamond chip started to be used to perform nanoscale NMR imaging and spectroscopy of nuclear species under ambient conditions [1]. These multifunctional quantum sensors provide the noninvasive methods to not only get the chemical composition of the molecules but also study the system dynamics in the nanoscopic volume above the diamond surface. The incredibly small size of the detection volume allows to study the membrane structure around each biomolecule individually.

Here we demonstrate the measurements of lateral diffusion of phospholipids in artificial vesicles modelling cell membranes on the top of diamond nanopillars through the correlation spectroscopy protocol. Pillar-shaped photonic structures hosting such NV centers enables not only significantly increase the photon flux in comparison to the bulk diamond, but also provide NMR measurements inside the vesicles.

[1] T. Staudacher, F. Shi, S. Pezzagna et al., Science 339, 561 (2013).