Dresden 2017 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 52: Topological Problems in the Physics of Polymers, Biopolymers and Fibers I (Joint Focus Session CPP/BP)

BP 52.1: Hauptvortrag

Donnerstag, 23. März 2017, 15:00–15:30, ZEU 260

Polymers in the cell nucleus — •Maria Barbi, Antony Lesage, and Jean-Marc Victor — Laboratoire de physique Theorique de la Matiere Condensee - UPMC - Paris VI - France

Understanding the genome functional architecture and its dynamics is one of the big challenges of systems biology. The three-dimensional arrangement, in the cell nucleus, of the protein-DNA assembly that constitutes chromosomes is expected to be crucial for the regulation of gene expression, hence cell differentiation and cell type setting. The rapid progress of experimental techniques Begins to make it possible to explore these complex structures. I will show how, when used in connection with experimental results, polymer physics represents a powerful tool in deciphering the chromosome arrangement and dynamics.