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BP: Fachverband Biologische Physik

BP 61: Topological Problems in the Physics of Polymers, Biopolymers and Fibers II (Joint Focus Session CPP/BP)

BP 61.4: Hauptvortrag

Freitag, 24. März 2017, 11:00–11:30, ZEU 222

Protein Folding under Mechanical Load — •Matthias Rief — Physikdepartment der TU München, James-Franck-Str. 85748 Garching

The development of nano-mechanical tools like AFM and optical traps has made it possible to address individual biomolecules and study their response to mechanical forces. These techniques allow us to study and induce conformational changes of proteins in real time. In my talk, I will show how single molecule mechanical methods can be used to study folding of proteins. Examples will include the folding of the calcium binding protein calmodulin, as well as the folding of a protein with knotted structure.