Dresden 2017 – scientific programme
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BP: Fachverband Biologische Physik
BP 7: Posters - Mechanics and Dynamics of 3D Tissues (Focus Session)
BP 7.3: Poster
Monday, March 20, 2017, 17:30–19:30, P3
Dynamics of fluid pumping through a thick epithelium — •Niladri Sarkar1, Jacques Prost2,3, and Frank Jülicher1 — 1Max Planck Institute for the Physics of Complex Systems — 2Institut Curie/CNRS — 3MBI, National University of Singapore
We study the dynamics of a thick epithelial tissue which pumps an interstitial fluid. We consider a tissue with average cell polarity normal to the tissue layer. The cell pumps fluid against a pressure difference. Using a two-component hydrodynamic continuum theory, we study the dependence of tissue stress, cell velocity and fluid flow on the the external fluid pressure and the cell pumping activity. We find that the existence of steady states depend strongly on the external pressure difference, the pumping activity and the properties of the interface seperating the tissue from the surrounding fluid.