Dresden 2017 – wissenschaftliches Programm
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DY: Fachverband Dynamik und Statistische Physik
DY 27: Posters - Statistical Physics Biological Systems
DY 27.4: Poster
Dienstag, 21. März 2017, 18:15–21:00, P3
Can one hear the length of an axon? — •Frederic Folz1, Lukas Wettmann1, Karsten Kruse2, and Giovanna Morigi1 — 1Department of Theoretical Physics, Saarland University, Saarbrücken, Germany — 2NCCR Chemical Biology, Department of Biochemistry, Department of Theoretical Physics, University of Geneva, Geneva, Switzerland
Axons are linear processes of nerve cells that can range from a few tens of micrometers up to meters in length. In addition to external cues, the length of an axon is also regulated by unknown internal mechanisms. Molecular motors have been suggested to generate oscillations with a length-dependent frequency that could be used to measure an axon's extension. Here, we present a mechanism that uses the oscillatory signal to regulate the axon length. We show that in addition to the frequency also the form of the oscillations contribute significantly to determining the steady state length.