Dresden 2017 – scientific programme

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MA: Fachverband Magnetismus

MA 35: Magnetic Particles / Clusters

MA 35.13: Talk

Wednesday, March 22, 2017, 12:30–12:45, HSZ 101

The effect of clustering of magnetic nanoparticles on sensing and imaging in medicine — •Ondrej Hovorka — University of Southampton, UK

In this talk we discuss the role of aggregation of magnetic nanoparticles on performance of biosensing methodologies based on magnetorelaxometry (MRX) and of magnetic particle imaging (MPI). Employing the kinetic Monte-Carlo modelling of fractal clusters of magnetic nanoparticles such as typically observed in intracellular environments [1], we show that depending on the structure of aggregates the performance in MRX and MPI can be downgraded or enhanced. We also illustrate various memory effects emerging in the time scale range from superparamagnetic to hysteresis regime and discuss their potential utilisation for optimising the MRX and MPI applications [2, 3]. Understanding the effects of aggregation of magnetic nanoparticles is becoming an increasingly important issue because it implies that optimal designs of magnetic nanostructures need to take into account the considerations of realistic environments.

References: [1] Etheridge et al., Technology 2, 214 (2014). [2] O. Laslett, et al., Applied Physics Letters 106, 012407 (2015). [3] H. Mamiya, B. Jeyadevan, PLoS ONE 10, e0118156 (2015).