Berlin 2018 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 10: Postersession II

BP 10.16: Poster

Montag, 12. März 2018, 17:30–19:30, Poster C

Design and construction of a magnetic trap for microrheological measurements — •Jonas Pfeil, Irina Schrezenmeier, Tobias Neckernuss, Daniel Geiger, Frederike Erb, Fabian Port, and Othmar Marti — Institute of Experimental Physics, Ulm University, Ulm, Deutschland

Today microrheological measurements on living cells using optical tweezers are scientific state of the art for analysis of cell mechanics. The maximum force that can be exerted on cells is limited by the maximum tolerable temperature of the cell. This limits the maximum forces to the nN range, which are too small to deform a whole cell significantly.

In contrast magnetic traps using superparamagnetic beads and high speed optical measurements do not heat the sample. Instead the limiting factors are magnetic flux and the gradient of the magnetic flux, which corresponds to the force on the beads. To achieve high gradient fields strong magnets can be used or the tip of the magnet has to be brought to the vicinity of the sample.

We will present solutions for the construction of a magnetic trap using a sharp tip and a single electromagnet using previously published designs adapted to our setup and our performance needs.