Berlin 2018 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 10: Postersession II

BP 10.28: Poster

Montag, 12. März 2018, 17:30–19:30, Poster C

Measurements and Simulations with the CellMOUSE device — •Jonas Pfeil, Tobias Neckernuss, Daniel Geiger, Ralf Schuster, and Othmar Marti — Institute of Experimental Physics, Ulm University

We recently developed a tool to characterize suspended cells passing an optical sensor, the so called CellMOUSE device. With this high speed optical setup we are able to determine different parameters like shape, size and morphology of the passing particles. These are important markers to distinguish different cells.
We will show measurements of various samples using the CellMOUSE device to show the range of possible applications. Besides investigations of well known samples for validation of the measurement principle, we also observe and distinguish cells of different origins in mixtures. Due to the real time nature of the experiment, we are able to manipulate single cells according to the measurement result. The technique can be also applied to other samples like bacteria or particles of different sizes.
To complete the study, we developed a simulation system for CellMOUSE to determine the figures of merit a priori.