Berlin 2018 – wissenschaftliches Programm

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BP: Fachverband Biologische Physik

BP 15: Postersession III

BP 15.73: Poster

Dienstag, 13. März 2018, 14:00–16:00, Poster B

Adding curvature to the vertex model of the Drosophila imaginal wing development. — •Joris Paijmans — MPI-PKS, Dresden, Germany

Vertex models describing the mechanics of epithelial cell tissues, have been very successful explaining the effect of planar cell polarity, cell elongation and topological transitions in the tissue. The fruit fly Drosophila has proven to be an excellent model organism to study tissue mechanics. In particular, the development of the wing of the fly, consisting of a double layer of cells, has been studied in great detail. This double layer forms in the pupal stage after the eversion (turning inside out) of the single layer imaginal wing disc. To understand the onset of eversion we require a vertex model that account for the curvature in the tissue, which was not possible in our previous description. I show how to make the 2D vertex model bend and how to describe the effect of curvature on the cell organization in the tissue.