Berlin 2018 – scientific programme

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BP: Fachverband Biologische Physik

BP 17: Cell Mechanics I

BP 17.8: Talk

Wednesday, March 14, 2018, 12:00–12:15, H 1058

Applications of new optical high speed cell characterization device CellMOUSE — •Daniel Geiger, Tobias Neckernuss, Jonas Pfeil, Ralf Schuster, and Othmar Marti — Institute of Experimental Physics, Ulm University

For various applications in science and medicine the identification of different cell parameters of suspended cells is essential. We developed a novel tool to assess important cellular parameters like size, shape and morphology in real time for more than 500 cells per second. This allows completely new experiments in various fields of basic research and clinical applications. After a brief introduction to the technique we present different applications of the so called CellMOUSE device. A validation for the measurement principle with well known samples will be shown. Furthermore, the determination of cellular parameters from suspended cells with superior throughput and accuracy will be presented. The samples range from simple NB4 cells to leukocytes and erythrocytes to bacteria and bacterial clusters. In addition we will present a simulation method for an easy comparison of our results with well established techniques.