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BP: Fachverband Biologische Physik

BP 9: Postersession I

BP 9.23: Poster

Montag, 12. März 2018, 17:30–19:30, Poster A

A novel water soluble iron phthalocyanine as a redox mediator integrated to multifunctional hydrogel based graphene nanoplatelet for glucose monitoring — •hadi al-sagur, komathi shanmugasundaram, and aseel hassan — Materials and Engineering Research Institute, Sheffield Hallam University, Sheffield, United Kingdom

Herein, we report a novel sensing platform for glucose biosensor applications. A three-dimensional multifunctional hydrogel interconnected network of water-soluble iron phthalocyanine (FePc) in single-layer graphene nanoplatelet (SLGNPs) for glucose oxidase (GOx) immobilization (PAA-FePc-SLGNPs/PANI /GOx-MFH) has been reported. Structural and morphological studies for (PAA-FePc-SLGNPs/PANI -MFH) were carried out using scanning electron microscopy (SEM), Fourier-Transform Infrared (FTIR), transmission electron microscopy, (TEM), X-ray diffraction (XRD), Raman spectroscopy and UV*Visible absorption spectroscopy. The electrochemical biosensor was fabricated utilizing PAA-FePc-SLGNPs/PANI -MFH as the enzyme immobilizing matrix coated on a screen-printed carbon electrode, and glucose oxidase (GOx) was used as a model enzyme. The electrical conductivity of the detection electrode was studied using electrochemical impedance spectroscopy (EIS). The modified electrodes were studied by amperometry and cyclic voltammetry. The PAA-FePc-SLGNPs/PANI /GOx-MFH was designed towards glucose monitoring with high sensitivity, good selectivity and low detection limit. Our biosensor could potentially be a valuable tool at the clinical uses for monitoring diabetes.