Berlin 2018 – wissenschaftliches Programm
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BP: Fachverband Biologische Physik
BP 9: Postersession I
BP 9.25: Poster
Montag, 12. März 2018, 17:30–19:30, Poster A
Effects of changing the Zeta potential of Graphene Quantum Dots for Biological Applications — •Stefanie Berger1, Stefan Fasbender1, Sebastian Bauer2, Stephan Schmidt2, Laura Hartmann2, and Thomas Heinzel1 — 1Heinrich Heine Universität Düsseldorf, Institut für Experimentelle Physik der kondensierten Materie — 2Heinrich Heine Universität Düsseldorf, Institut für Organische und Makromolekulare Chemie
Fluorescent graphene quantum dots (GQDs) are prepared by thermal decomposition of citric acid and diethylenetriamine slightly modifying the method of Qu et al. [1]. The concentration dependent fluorescence properties are studied with fluorescence spectroscopy and the Zeta potential is measured using dynamic light scattering. Both is compared to GQDs with modified features. Possible modifications include the binding of a positive charged amide or a slight change of the GQD recipe. In order to analyse the particles' properties for biological applications, their uptake into primary human blood cells and their nucleus is investigated using flow cytometry and visualised via confocal microscopy.
[1] Qu et al., Light: Science & Applications, 2015, 4, e364