Berlin 2018 – scientific programme

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BP: Fachverband Biologische Physik

BP 9: Postersession I

BP 9.3: Poster

Monday, March 12, 2018, 17:30–19:30, Poster A

Dielectric spectroscopy of bovine serum albumin at GHz frequencies — Eva-Maria Laux, Jessica Gibbons, Elena Ermilova, Frank F. Bier, and •Ralph Hölzel — Fraunhofer Institute for Cell Therapy and Immunology, Branch Bioanalytics and Bioprocesses, Potsdam, Germany

In recent years electronic components have become available reaching the upper GHz range. This makes this frequency range accessible for novel biomedical applications. Still, detailed knowledge about the properties of biological materials at these frequencies is missing, and the interaction mechanisms with such electromagnetic fields are often unclear. Here we present an experimental system based on a vector network analyser for the temperature controlled determination of the dielectric properties of biomolecules. The influence of protein concentration, of temperature and of denaturing agents on aqueous solutions of bovine serum albumin (BSA) is presented between 10 MHz and 110 GHz. Further work aims at reducing sample size and improving accuracy.