Berlin 2018 – scientific programme
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DY: Fachverband Dynamik und Statistische Physik
DY 27: Microfluidics
DY 27.1: Talk
Tuesday, March 13, 2018, 11:15–11:30, BH-N 128
Antimargination of microparticles and platelets in branching vessels — •Christian Bächer1, Lukas Schrack1,2, and Stephan Gekle1 — 1Biofluid Simulation and Modeling, Bayreuth, Germany — 2Bio and Nano Physics, Innsbruck, Austria
A mixed suspension of red blood cells and microparticles flows through complex geometries typical for in vivo vessel networks: a vessel confluence and a bifurcation. Our three-dimensional Lattice-Boltzmann simulations show strong effects on cell and particle distribution: behind a confluence we observe an additional, surprisingly stable cell-free layer in the center containing microparticles undergoing anti-margination. In contrast to the perturbed margination in vessel confluence, we obtain full microparticle margination in branching vessels. Margination in branching vessels and antimargination behind confluences may explain in vivo findings of strongly different platelet distribution in arterioles (mainly bifurcations) and venules (mainly confluences).