Berlin 2018 – wissenschaftliches Programm

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DY: Fachverband Dynamik und Statistische Physik

DY 44: Pattern Formation I

DY 44.9: Vortrag

Mittwoch, 14. März 2018, 12:45–13:00, BH-N 334

Influence of fast advective flows on pattern formation of Dictyostelium discoideum — •Torsten Eckstein, Estefania Vidal, Albert Bae, Vladimir Zykov, Eberhard Bodenschatz, and Azam Gholami — Max Planck Institute for Dynamics and Self-Organization, Goettingen, Germany

We report experimental and numerical results on pattern formation of self-organizing Dictyostelium discoideum cells in a microfluidic setup under a constant buffer flow. The external flow advects the signaling molecule cyclic adenosine monophosphate (cAMP) downstream, while the chemotactic cells attached to the solid substrate are not transported with the flow. At high flow velocities, elongated cAMP waves are formed that cover the whole length of the channel and propagate both parallel and perpendicular to the flow direction. While the wave period and transverse propagation velocity are constant, parallel wave velocity and the wave width increase linearly with the imposed flow. We also observe that the acquired wave shape is highly dependent on the wave generation site and the strength of the imposed flow. We compared the wave shape and velocity with numerical simulations performed using a reaction-diffusion model and found excellent agreement. These results are expected to play an important role in understanding the process of pattern formation and aggregation of D. discoideum that may experience fluid flows in its natural habitat.