Berlin 2018 – wissenschaftliches Programm

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DY: Fachverband Dynamik und Statistische Physik

DY 70: Poster: Flows, Patterns, Delay, Reaction Diffusion

DY 70.24: Poster

Donnerstag, 15. März 2018, 15:30–18:00, Poster A

Modeling of the Chemotatic Response of Amoeboid Cells with a Phase Field Model — •Eduardo Moreno¹, Francesc Font¹, Carsten Beta², and Sergio Alonso¹ — ¹Department of Physics, Universitat Politecnica de Catalunya, Barcelona, Spain — ²Institute of Physics and Astronomy, Universität Potsdam, Potsdam, Germany

Cells are able to polarize and move following gradients of chemical concentrations. The receptors of the cells induce an internal signal which produce the formation of localized regions of the cell with high concentrations of certain biochemicals which drive the locomotion of cells. We apply a phase field for the description of the interior (where the polarization processes evolve) and the exterior of the cells (where the chemicals diffuse) to model the two types of dynamics and the interaction of both environments at the membrane of the cell. We compare the resulting dynamics of the computer models with experiments of the motion of Dictyostelium discoideum following chemical gradients of the chemo-attractant cAMP (cyclic adenosine monophosphate).